Hyperuricaemia, gout and allopurinol in the CKD Queensland registry

Hyperuricaemia and gout.

Gout is increasing in prevalence throughout the world, particularly in developed countries. The causes are dietary--purine-rich foods, high saturated fats, fructose-containing drinks and alcohol. Gout is also drug-related and associated with increased obesity, hypertension, insulin resistance and metabolic syndrome. Although very readily treated, there is evidence that physicians fail to optimi...

Comparative trial of azapropazone and indomethacin plus allopurinol in acute gout and hyperuricaemia.

This study compared the effects of azapropazone and indomethacin plus allopurinol in the management of acute gout and hyperuricaemia. A group of 93 patients predominantly based in general practice were randomly allocated to the two treatment regimens (azapropazone (days 1-225) or indomethacin (1-28) followed by allopurinol (29-225)) on a double-blind double dummy basis. Azapropazone produced a ...

Total fasting, hyperuricaemia and gout.

The purpose of this communication is to draw attention to the apparently harmless hyperuricaemia which results from treating obese patients by total fasting. In such patients there is a progressive fall in the glomerular filtration rate during the fasting period resulting in the renal retention of urate (Murphy & Shipman, 1964). In addition there is competition between the ketone bodies and ura...

Sulphobromophthalein retention in gout and asymptomatic hyperuricaemia.

Methods BSP excretion tests were performed on 73 patients with gout (defined as recurrent acute arthritis associated with an elevated serum uric acid level),* sixteen patients with asymptomatic hyperuricaemia not due to renal failure, and thirty control subjects who were either hospital patients (none of whom had known liver disease, gout, or hyperuricaemia) or healthy volunteers. The details o...

Leaders Hyperlipidaemia in hyperuricaemia and gout